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Cognitive HEalth and Neurodegeneration
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Cognition | Brain | Aging | Neuroimaging
Regional tau deposition reflects different pathways of subsequent neurodegeneration and memory decline in cognitively normal older adults
Early tau deposition independent of amyloid predicts hippocampal atrophy that leads to memory deficits in normal aging, whereas elevated cortical tau is associated with cortical thinning that can lead to more severe memory decline in AD.
